Looking to absolutely demolish everything in Borderlands 4? The Vex Incarnate build is hands down one of the most overpowered setups in the game, capable of dealing billions in damage through stacking critical hit multipliers and kinetic status effects. This Siren build turns Vex into an unstoppable damage-dealing monster that can shred through Ultimate Vault Hunter Rank 5 content like it’s normal mode.
If you’re ready to break the game with ridiculous DPS numbers, here’s everything you need to know about building the perfect Incarnate Vex.
The Vex Incarnate build revolves around one core mechanic: stacking Bleed effects from critical hits to create exponentially scaling damage. When properly executed, this build can:
Stack damage multipliers infinitely through critical hit chains
Reach billions in damage against bosses and tough enemies
Dominate endgame content including Ultimate Vault Hunter Rank 5
Self-sustain through lifesteal and health restoration mechanics
Maintain constant uptime on powerful kill skills even during boss fights
The secret sauce is the Bloodletter skill combined with Throwing Knife Ordnance that makes every hit a critical hit, allowing you to stack Bleed effects to absurd levels.
Essential Vexcalation Skill Tree Build
The foundation of this build lies heavily in the Vexcalation skill tree, focusing on kill skills and critical hit synergies. Here’s your priority skill allocation:
Core Damage Skills (Max Priority):
Bloodletter (5/5) – The build enabler
Critical hits apply Bleed (Kinetic status effect)
Stacks up to 20 times for massive damage over time
Affected by status effect chance and damage bonuses
Grave Sights (5/5) – Critical hit amplifier
Kill skill that increases critical hit damage and gun handling
Essential for scaling your damage multipliers
Material Components (4/5) – Kinetic damage booster
Increases both direct kinetic damage and kinetic status effects
Directly amplifies your Bleed damage
Kill Skill Amplifiers:
Grave Power (3/3) – Stack multiplier
Increases maximum stacks on all kill skills
Nearly doubles the effectiveness of your kill skills
Grave Implements (5/5) – Gun damage boost
20% gun damage per stack (max 3 stacks with Grave Power)
Consistent damage increase for sustained fights
Grave Fiends (5/5) – Universal damage boost
Increases all damage dealt per kill skill stack
With Grave Power, provides up to 70% total damage increase
Sustain and Utility:
Leeching Attunement (1/5) – Survivability
Provides lifesteal when attuned to Kinetic
Includes reload speed bonus for better DPS uptime
Sanguine Fiends (1/5) – Health restoration
Restores health on kills or kill skill activation
Works with Mortal Terror for boss fight sustain
Fire Rate and Damage Scaling:
Drink Full (5/5) – Attack speed scaling
Stacks up to 50 times for 30% fire rate increase
Maintained through consistent gun damage
Grave Assault (1/5) – Additional fire rate
9% fire rate boost from kill skills (enhanced by Grave Power)
Combines with Drink Full for nearly doubled fire rate
Critical Hit Consistency:
Mortal Terror (5/5) – Kill skill activation
Chance to activate kill skills on critical hits
Essential for maintaining stacks during boss fights with few adds
Eldritch Blast/Phase Explosion refills ammo completely
Grants gun damage stacks that persist after Incarnate ends
Combines damage dealing with resource management
Vibe Check (Capstone) – Enhanced versatility
Makes Eldritch Blast a 3-charge skill with ricochet
Doubles cooldown reduction from gun damage
Allows ranged action skill usage
Defensive Utility:
Strike Me Down (1/1) – Échappement de secours
Automatic Second Wind every 120 seconds
Includes invisibility and Phase Explosion damage
Ultimate “get out of jail free” card
Cold Iron (5/5) & Portents of Suffering (3/5) – Damage amplifiers
Straight gun damage increases
Enhanced status effect damage for bigger Bleeds
The Throwing Knife Strategy (Build Enabler)
The key to making this build absolutely broken is the Throwing Knife Ordnance with Penetrator Augment. This combination transforms the build from good to game-breaking:
How the Combo Works:
Penetrator Augment makes ANY damage to the target count as a critical hit
Throw the knife, then unload your weapon for guaranteed critical hits
Each critical hit has a chance to apply Bleed via Bloodletter
Bleed stacks up to 20 times, creating exponential damage scaling
Re-throw the knife to refresh critical hit status and continue stacking
Execution Strategy:
Engage target with Throwing Knife (Penetrator)
Unload magazine for guaranteed critical hits and Bleed stacks
Re-throw knife to maintain critical hit status
Répéter until target is eliminated
Use against groups by bouncing between enemies
This strategy works on everything from basic psychos to endgame bosses, making even Ultimate Vault Hunter Rank 5 content manageable.
Best Weapons and Gear Setup
Primary Weapon: Armored Bod Legendary Shotgun
Emplacement de la ferme : Axemaul boss at The Toil of Spoiling Vis Auger Mine, Carcadia District, Dominion
While the core Incarnate build is incredibly powerful, you can adapt it for different playstyles:
Weapon Variations:
Kinetic SMGs for higher fire rate applications
Kinetic Assault Rifles for medium-range versatility
Multiple weapon types to stack Armored Bod’s multi-type bonuses
Defensive Variations:
Increased health investment for hardcore players
Shield-focused gear for more conservative playstyles
Bonus de vitesse de déplacement pour les tactiques de délit de fuite
Specialization Alternatives:
More Killer investment for pure status effect focus
Different firmware combinations based on available gear
Hybrid approaches mixing other Vex builds
For other powerful Vex build options, check out our character-specific guides in the Best Solo Class Guide.
Final Thoughts: Mastering the Incarnate
The Vex Incarnate build represents peak Borderlands 4 optimization – a perfect storm of skill synergies, gear interactions, and mechanical mastery. While it requires some practice to execute perfectly, the payoff is incredible: a build capable of trivializing even the game’s most challenging content.
Remember that mastering this build is a journey. Start with the core skills and concepts, gradually add complexity as you become comfortable with the mechanics, and don’t be afraid to experiment with variations that suit your playstyle.
Et ensuite :
Practice the Throwing Knife combo dans divers scénarios de combat
Farm for optimal gear using our specialized farming guides
Expérimentez différentes combinaisons d'armes to find your preferences
Tackle progressively harder content to test your build’s limits
With the Incarnate build in your arsenal, you’re ready to show the galaxy exactly why Sirens are the most feared Vault Hunters in the universe!
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Sacheen Chavan
Sacheen Chavan est un passionné de jeux vidéo, créateur de contenu et passionné de technologie, fort de plus de six ans d'expérience dans l'industrie du jeu vidéo. Il a contribué à des plateformes comme BollywoodFever et Buzzing Bulletin, où il a partagé ses analyses sur les tendances du jeu vidéo, l'e-sport et les dernières nouveautés en matière de matériel.
Connu pour ses critiques honnêtes et ses conseils pratiques, Sacheen aide les joueurs à améliorer leur expérience, qu'il s'agisse de dominer la scène e-sport, de s'attaquer aux RPG ou de tester des technologies de pointe. Il allie expérience pratique et passion pour le contenu communautaire.