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    Home›Resident Evil Requiem›How to Open the Organ Transport Box in Resident Evil Requiem [Puzzle Solution]
    Resident Evil Requiem Guide

    How to Open the Organ Transport Box in Resident Evil Requiem [Puzzle Solution]

    By Eva Roberts · February 27, 2026 · 13 min read
    artificial lungs in resident evil requiem
    Organ Transport Box Resident Evil Requiem

    The Organ Transport Box is one of the trickiest item puzzles in Resident Evil Requiem. You find it sitting inside a freezer van in the Garage of the Rhodes Hill Care Center, but there is no obvious way to open it — just a confusing set of dials, switches, and buttons on the back panel. The box contains the Artificial Lungs, one of two organs you need to reanimate the corpse in the Examination Room and obtain the Level 2 Wristband. This guide shows you the exact location of the Organ Transport Box, the complete step-by-step puzzle solution, where to find the in-game clue, and what to do with the Artificial Lungs once you have them.

    ???? Table of Contents

    1. Quick Answer: Puzzle Solution
    2. Where to Find the Organ Transport Box
    3. Surviving the Garage Bulldozer Encounter
    4. Where to Find the In-Game Clue (Leatherbound Notebook)
    5. How to Open the Organ Transport Box (Full Solution)
    6. Reward: Artificial Lungs
    7. What to Do After Getting the Artificial Lungs
    8. Frequently Asked Questions

    ⚡ Quick Answer: Organ Transport Box Solution

    Examine the box from your inventory → flip it over and remove the back panel → turn the circular dial from AUTO to HAND → move the right slider to the middle position → toggle Switch 5 down → toggle Switch 2 down → turn the dial back from HAND to AUTO. The box opens, revealing the Artificial Lungs.

    Where to Find the Organ Transport Box

    The Organ Transport Box is located in the Garage on the 1st floor of the West Wing in the Rhodes Hill Care Center. It is sitting inside an open freezer van at the very back of the Garage.

    To reach the Garage, you need to pass through the Level 1 Security Door in the West Wing corridor (past the Kitchen area). This requires the ID Wristband (Level 1). After passing through the security door, the Garage is located south of the Custodian’s Office.

    The Organ Transport Box inside the freezer van at the back of the Garage

    Walk to the back of the Garage and interact with the van to pick up the Organ Transport Box. It will be added to your inventory as a key item. However, be ready for a fight immediately after grabbing it — picking up the box triggers a dangerous combat encounter.

    Save First

    The Custodian’s Office next to the Garage has a typewriter (save point). Save your game there before entering the Garage, especially on higher difficulties. Also pick up the Wrench from the desk while you are there — you will need it for the Cold Storage door.

    Surviving the Garage Bulldozer Encounter

    The moment you pick up the Organ Transport Box and turn to leave, an infected zombie driving a bulldozer will crash through the opposite wall and charge directly at Grace. This is a scripted encounter and you cannot avoid it.

    How to Survive

    Immediately aim for the driver’s head. A few pistol headshots will kill the zombie behind the wheel, stopping the bulldozer.

    Once the driver is dead, the bulldozer will stop. Crawl over or around the vehicle to exit the Garage.

    Check the newly accessible area to the right of the bulldozer’s crash path — there are breakable boxes with handgun ammo and possibly healing items.

    Insanity Difficulty Warning

    On Insanity difficulty, killing the driver alone is not enough. You also need to shoot the flaming area under the bulldozer’s plow to stop it from continuing to move forward. Be prepared to use more ammo on this difficulty.

    Where to Find the In-Game Clue (Leatherbound Notebook)

    The game provides the solution to the Organ Transport Box puzzle through a document called “Unlocking the Organ Transport Box”. This document is found inside the Leatherbound Notebook, which you receive by solving the Sun Puzzle Box in the Lead Researcher’s Office.

    Here is how you obtain the clue through normal gameplay:

    Get the Corrosive from the Conference Room to destroy the Sturdy Padlock on the Sun Puzzle Box.

    Enter the code Star – Sun – Moon – Sun to open the puzzle box.

    Collect the Sun Quartz and the Leatherbound Notebook from inside.

    Inspect the Leatherbound Notebook in your inventory. One of the files inside is titled “Unlocking the Organ Transport Box” — it contains a diagram showing the exact switch and dial positions required.

    You Don’t Actually Need the Clue to Open the Box

    You can open the Organ Transport Box the moment you pick it up from the Garage, even if you have not yet found the Leatherbound Notebook. The puzzle does not check whether you have the document — it just requires you to set the switches in the correct positions. Use our solution below if you want to skip ahead.

    Storage Tip

    The Leatherbound Notebook stays in your inventory as a key item after you pick it up. Once you have read the Organ Transport Box instructions, you can deposit the notebook in the Storage Box to free up an inventory slot. You do not need to carry it.

    How to Open the Organ Transport Box (Full Solution)

    Open your inventory, select the Organ Transport Box, and choose Examine. Rotate the box so you can see the back panel, then interact with it to remove the panel and reveal the puzzle mechanism underneath.

    You will see three types of controls: a circular dial (bottom center) with AUTO and HAND positions, a vertical slider (right side) with three positions, and five small numbered switches in a row. The solution must be performed in the correct order:

    ???? Organ Transport Box — Puzzle Solution

    1Circular Dial
    Turn the dial from AUTO to HAND
    2Right Slider
    Move the vertical slider to the middle position (second notch)
    3Switch 5
    Toggle the 5th switch (rightmost) down
    4Switch 2
    Toggle the 2nd switch from the left down

    Final Step: Turn the circular dial back from HAND to AUTO. The latches on top release and the box opens.

    Organ Transport Box puzzle solution showing correct switch and dial positions in Resident Evil Requiem

    The correct switch and dial positions to open the Organ Transport Box

    Reset Button

    If you set any control in the wrong order or wrong position, look for the Reset button on the puzzle interface. Pressing it reverts all dials and switches back to their default positions so you can start over cleanly. You can reset as many times as you need without penalty.

    Once the final dial is turned back to AUTO, the top latches will click open. Interact with the top of the box to lift the lid and collect the Artificial Lungs inside.

    Reward: Artificial Lungs

    Artificial Lungs obtained from the Organ Transport Box in Resident Evil Requiem

    The Artificial Lungs — one of two organs needed for the Examination Room corpse puzzle

    ItemPurpose
    Artificial Lungs One of two artificial organs needed to reanimate the Organless Corpse in the Examination Room. The other organ required is the Artificial Heart, found in Cold Storage. Both organs must be inserted into the corpse to obtain the ID Wristband (Level 2).

    The Artificial Lungs take up one inventory slot. If your inventory is full, deposit items at the Storage Box in the Guard Office (East Wing) or the Custodian’s Office (West Wing) before opening the Organ Transport Box.

    What to Do After Getting the Artificial Lungs

    With the Artificial Lungs in hand, you are halfway to completing the Organless Corpse puzzle. Here is the complete path forward:

    If you have not already, get the Artificial Heart from Cold Storage in the West Wing. You will need the Wrench from the Custodian’s Office to open the Cold Storage door.

    Take both the Artificial Lungs and Artificial Heart to the Examination Room in the East Wing.

    Interact with the Organless Corpse on the operating table. Insert both organs (the order does not matter).

    The corpse will reanimate and attack. Aim for the head — after a short fight, it will collapse on its own.

    Loot the ID Wristband (Level 2) from the fallen zombie’s body.

    Use the Level 2 Wristband to unlock the Isolation Ward door in the East Wing (green-lit lock between the Blood Lab and Waiting Room).

    Proceed through the Isolation Ward to the Security Manager’s Office and begin obtaining the final Star Quartz to complete your escape from the Care Center.

    Blisterhead Warning

    When you return to the Examination Room after the corpse fight, be careful — the other zombie that was on the adjacent operating table earlier may have mutated into a Blisterhead. These are faster and deal more damage than standard zombies. Give it a wide berth or eliminate it quickly.

    Before heading to the Isolation Ward, take a moment to check off other tasks: open the Examination Room Safe (Right 30 – Left 10 – Right 50 on Standard) for three Antique Coins, and make sure you have collected the Care Center Fuse if you have not done so already.

    Frequently Asked Questions

    Where is the Organ Transport Box in Resident Evil Requiem?

    Inside a freezer van at the back of the Garage in the West Wing. You need the ID Wristband (Level 1) to access the Garage area through the Level 1 Security Door past the Kitchen.

    What is the solution to the Organ Transport Box puzzle?

    Examine the box → remove the back panel → turn dial from AUTO to HAND → move right slider to middle → toggle Switch 5 down → toggle Switch 2 down → turn dial from HAND to AUTO. The box opens.

    Do I need the Leatherbound Notebook to open the box?

    No. The notebook contains the in-game clue, but the puzzle can be solved at any time without having the document. You can open the box the moment you pick it up if you already know the solution.

    Where do I find the Leatherbound Notebook?

    Inside the Sun Puzzle Box in the Lead Researcher’s Office, along with the Sun Quartz. You need the Corrosive to destroy the padlock first.

    What happens if I set the switches in the wrong order?

    The box will not open, but nothing bad happens. Press the Reset button on the puzzle interface to revert everything to default, then try again.

    What is the Artificial Lungs used for?

    Together with the Artificial Heart (from Cold Storage), the Artificial Lungs are inserted into the Organless Corpse in the Examination Room. This reanimates the corpse, and defeating the resulting zombie gives you the ID Wristband (Level 2).

    Is the puzzle solution the same on Insanity difficulty?

    Yes. The Organ Transport Box solution is identical on all difficulties. Only safe codes change between Standard and Insanity in Resident Evil Requiem.

    How do I survive the bulldozer in the Garage?

    Immediately shoot the zombie driver in the head when the bulldozer charges. On Insanity, you also need to shoot the flaming area under the plow to fully stop the vehicle.

    ???? More Resident Evil Requiem Guides

    RE Requiem: How to Destroy the Sturdy Padlock RE Requiem: How to Open the Door Without Handwheel RE Requiem: Level 1 ID Wristband Location RE Requiem: Examination Room Safe Code RE Requiem: Bar & Lounge Safe Code RE Requiem: East Wing Keycard Location RE Requiem: Chairman’s Office Puzzle Box Solution RE Requiem: West Wing Keycard Location RE Requiem: Care Center Fuse Location

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